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Elevated C-reactive protein is associated with sensory gating deficit in schizophrenia
Sensory and cognitive impairments and inflammatory processes are contributing factors to the pathogenesis of schizophrenia. A previous study found that an elevated CRP level (≥ 5 mg/L) ... [Read More]
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Mild cognitive impairment is prevalent in persons with severe obesity
Objective This study examines the prevalence of mild cognitive impairment (MCI) in a sample of adults with severe obesit... [Read More]
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Possible association between social cognition and metabolic dysfunctions in Bipolar Disorder and Schizophrenia: Preliminary results
Highlights•Metabolic abnormalities are more frequent in psychotic patients.•Metabolic syndrome and obesity have been associated with cognitive deficits.•Schizophrenic and Bipolar patients show deficit... [Read More]
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Multiple Antipsychotic Medication Prescribing Patterns
To assess current prescribing practices regarding concomitant use of antipsychotic medications and summarize the reasons clinicians may prescribe >1 scheduled agent.METHODS:The pharmacy ide... [Read More]
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Comparison of depression symptoms between primary depression and secondary-to-schizophrenia depression: International Journal of Psychiatry in Clinical Practice: Vol 21, No 4
Objectives: This study exclusively aimed to clinically assess which symptom pattern discriminates primary depression from depression-secondary to-schizophrenia.Methods: A total of 98 patients wi... [Read More]
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Prepulse inhibition in first-degree relatives of schizophrenia patients: A systematic review
Prepulse inhibition (PPI) is a measure of sensorimotor gating used to identify deficits in early-stage information processing and inhibitory function defects. Many studies support the presence of ... [Read More]
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Are we studying and treating schizophrenia correctly?
New findings are rapidly revealing an increasingly detailed image of neural- and molecular-level dysfunction in schizophrenia, distributed throughout interconnected cortico–striato–pallido–thalamic ... [Read More]
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The Genetics of Schizophrenia
Research into the etiology of schizophrenia, particularly the possible genetic basis, has never been as interesting and as provocative as in the past three years. Sullivan looks critically at the key ... [Read More]
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Predicting bipolar disorder and schizophrenia based on non-overlapping genetic phenotypes using deep neural network
Earlier this week I stumbled across a Python library with a pretty compelling value proposition. This library is called Diagrams, and as its namesake states it creates diagrams. These diagrams that… [Read More]
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Predicting bipolar disorder and schizophrenia based on non-overlapping genetic phenotypes using deep neural network | SpringerLink
Computational Psychiatry is an emerging field of science. It focuses on identifying the complex relationship between the brain’s neurobiologyComputational Psychiatry is an emerging field of science. I... [Read More]
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Sparse deep neural networks on imaging genetics for schizophrenia case–control classification
Deep learning methods hold strong promise for identifying biomarkers for clinical application. However, current approaches for psychiatric classification or prediction do not allow direct interpre... [Read More]
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Effects of oxytocin and genetic variants on brain and behaviour: Implications for treatment in schizophrenia
While initial findings from OXT single dose/clinical trial studies are promising, more interdisciplinary research in both healthy and psychiatric populations is needed before determining whether ... [Read More]
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The Stigmatising Implications of Presenting Schizophrenia as a Genetic Disease | SpringerLink
This study aimed to investigate the hypothesis that belief in a genetic aetiology of schizophrenia will increase the stigma associated with the disorder. It is also possible that individuals with a d... [Read More]