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Diabetes and development of tardive dyskinesia
Examined 160 elderly individuals (aged 55+ yrs) who were beginning neuroleptic treatment and determined that 24 had diabetes and 136 did not. After 43 wks of neuroleptic exposure, the cumulative... [Read More]
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Frontiers | 5-Hydroxytryptamine Receptors and Tardive Dyskinesia in Schizophrenia | Molecular Neuroscience
Background Tardive dyskinesia (TD) is a common side effect of antipsychotic treatment. This movement disorder consists of orofacial and limb-truncal components. The present study is aimed at investiga... [Read More]
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Estrogen Receptor Activation and Tardive Dyskinesia
Estrogen Receptor Activation and Tardive Dyskinesia Estrogen's multimodal role in the central nervous system may prove useful for the amelioration or prevention of TD. All the evidence sugg... [Read More]
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Association between the IL10 rs1800896 Polymorphism and Tardive Dyskinesia in Schizophrenia
This finding suggests that the A allele of rs1800896 may be associated with TD development following a low IL-10 function. [Read More]
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Parkinson disease: not just a movement disorder.
Nonmotor symptoms are common in Parkinson disease and can significantly worsen the health and quality of life of the patient and family members. These symptoms can be broadly categorized as sensory, a... [Read More]
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A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor | PNAS
A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor | PNAS [Read More]
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Tardive Dyskinesia: Therapeutic Options for an Increasingly Common Disorder | SpringerLink
Tardive dyskinesia (TD) is a serious, often disabling, movement disorder that is caused by medications that block dopamine receptors (i.e., neuroleptics, a [Read More]
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Frontiers | Association Study of the Complement Component C4 Gene in Tardive Dyskinesia | Pharmacology
Tardive Dyskinesia (TD) is a movement disorder that may develop in schizophrenia patients being treated long-term with antipsychotic medication. TD interferes with voluntary movements and leads to sti... [Read More]
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One bout of neonatal inflammation impairs adult respiratory motor plasticity in male and female rats | eLife
A single neonatal inflammatory event induces long-term impairments in two forms of adult respiratory motor plasticity, an important aspect of the control of breathing for compensation after injury or ... [Read More]
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Reflex memory theory of acquired involuntary motor and sensory disorders | SpringerLink
Explicit and implicit memories are conserved but flexible biological tools that nature uses to regulate the daily behaviors of human beings. An aberrant form of the implicit memory is presumed to exis... [Read More]
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Models of hyperkinetic disorders in primates
Hyperkinetic movement disorders include tremors, dystonia, chorea and stereotypies.•Models of these conditions exist in non-human primates, often with high translational value.•Several species are use... [Read More]
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Animal models of tardive dyskinesia--a review.
Tardive dyskinesia is a serious motor side effect of long term neuroleptic therapy, with an unknown pathophysiological basis. The leading hypothesis of the pathophysiology of tardive dyskinesia includ... [Read More]
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Effects of Levetiracetam on Tardive Dyskinesia: A Randomized, Double-Blind, Placebo-Controlled Study | Psychiatrist.com
Levetiracetam appeared effective for TD in this study. The mechanisms of its therapeutic effect are unclear but may involve reducing neuronal hypersynchrony in basal ganglia. Future studies should att... [Read More]
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PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice
CBD attenuated orofacial dyskinesia and cognitive impairment induced by haloperidol.•CBD reduced striatal and hippocampal levels of IL-1β and TNF-α induced by haloperidol.•Behavioral effects of CBD we... [Read More]