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Tardive Dyskinesia Development, Superoxide Dismutase Levels, and Relevant Genetic Polymorphisms
Tardive dyskinesia (TD) is a prevalent movement disorder that significantly impacts patients with schizophrenia (SCZ) due to extended exposure to antipsychotics (AP). Several genetic polymorphisms, in... [Read More]
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Involvement of adenosinergic receptor system in an animal model of tardive dyskinesia and associated behavioural, biochemical and neurochemical changes
AbstractTardive dyskinesia is a syndrome characterized by repetitive involuntary movements usually involving the mouth, face and tongue. It is considered as the late onset adverse effect of prol... [Read More]
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Tardive dyskinesia is caused by maladaptive synaptic plasticity: A hypothesis
Abstract It has been 50 years since the first patients with tardive dyskinesia (TD) were described, but the pathophysiology is only partially understood a... [Read More]
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A systematic review on the use of clozapine in treatment of tardive dyskinesia and tardive dystonia in patients with psychiatric disorders | SpringerLink
RationaleThough clozapine is recommended for treatment of tardive dyskinesia (TD) relating to the use of antipsychotic medications, studies comprehensively investigating the treatment effect of ... [Read More]
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A Patient with Tardive Dyskinesia Treated with Tetrabenazine: Case Report
AbstractTypical antipsychotics exert their effects through D2 receptors. If too many D2 receptors are blocked in the nigrostrital pathway, movement disorders occur. If D2 blockade in the nigrost... [Read More]
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Tardive Dyskinesia and Long-Acting Injectable Antipsychotics: Analyses Based on a Spontaneous Reporting System Database in Japan
ABSTRACT Objective: This study compared the reporting frequency of tardive dyskinesia (TD) between long-acting injectable antipsychotics (LAI-APs) and the equivalent oral antipsychotics (O-APs)... [Read More]
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Diagnostics | Free Full-Text | Genes of the Glutamatergic System and Tardive Dyskinesia in Patients with Schizophrenia
Background: Tardive dyskinesia (TD) is an extrapyramidal side effect of the long-term use of antipsychotics. In the present study, the role of glutamatergic system genes in the pathogenesis of total T... [Read More]
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"The Effect of VMAT2 Inhibitors on Tardive Dyskinesia Symptoms in patie" by Ada Kelly
Prior to the FDA approval of VMAT2 inhibitors for the treatment of tardive dyskinesia (TD), few concrete treatment options were available for TD. The most common management strategy would include swit... [Read More]
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A Sentiment Analysis of Unstructured Electronic Medical Record Data of Patients Treated With Vesicular Monoamine Transporter 2 Inhibitors in Huntington’s Disease and Tardive Dyskinesia (P3-11.006) | Neurology
Objective: To assess sentiment of clinical outcomes reported in unstructured electronic medical record (EMR) data of patients with Huntington’s disease (HD) or tardive dyskinesia (TD) treated wi... [Read More]
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Long-term effects of pallidal deep brain stimulation in tardive dystonia: a follow-up of 5–14 years | SpringerLink
IntroductionPallidal DBS is an established treatment for severe isolated dystonia. However, its use in disabling and treatment-refractory tardive syndromes (TS) including tardive dyskinesia... [Read More]
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Defining utility values for patients with tardive dyskinesia
To measure health state preferences and estimate utility values for tardive dyskinesia (TD) from the perspective of the US general population, accounting for factors affecting quality of life (QOL).Me... [Read More]
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Dysfunctional monocytic toll-like receptor 4 signaling pathway and cognitive deficits in chronic schizophrenia patients with tardive dyskinesia
Highlights•Both TD and NTD patients showed higher TLR4 signal pathway activity at baseline but weaker responses to lipopolysaccharide (LPS), as compared to healthy contro... [Read More]
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Tardive dyskinesia update: treatment and management | BJPsych Advances | Cambridge Core
Tardive dyskinesia update: treatment and management - Volume 25 Issue 2BOX 1 The major pathophysiological theories of tardive dyskinesia aetiology Postsynaptic D2 receptor supersensitivity Upregulatio... [Read More]
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Once-Daily Valbenazine Is Effective for Tardive Dyskinesia in Elderly Patients (>=65 Years)
Once-Daily Valbenazine Is Effective for Tardive Dyskinesia in Elderly Patients (>=65 Years)Author links open overlay panelMarthaSajatovicMD1 KhodyFarahmandPharmD2 ChiragShahPharmD2 LeslieLundt MD2h... [Read More]