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Inferior Frontal Cortex Modulation with an Acute Dose of Heroin During Cognitive Control | Neuropsychopharmacology
Impairments in inhibitory control and in stimulus-driven attention are hallmarks of drug addiction and are associated with decreased activation in the right inferior frontal gyrus (IFG). Although prev... [Read More]
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Decreased dopamine activity predicts relapse in methamphetamine abusers | Molecular Psychiatry
Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted detoxification. However, the extent to which striatal DA function in M... [Read More]
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A systematic review and narrative synthesis of data-driven studies in schizophrenia symptoms and cognitive deficits | Translational Psychiatry
To tackle the phenotypic heterogeneity of schizophrenia, data-driven methods are often applied to identify subtypes of its symptoms and cognitive deficits. However, a systematic review on this topic i... [Read More]
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Integrative Neuroscience | Neuropsychopharmacology
   A fundamental impediment to an ‘Integrative Neuroscience’ is the sense that scientists building models at one particular scale often see that scale as the epicentre of all brain func... [Read More]
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Methamphetamine Activates Reward Circuitry in Drug Naïve Human Subjects | Neuropsychopharmacology
Amphetamines are highly addictive drugs that have pronounced effects on emotional and cognitive behavior in humans. These effects are mediated through their potent dopaminergic agonistic properties. D... [Read More]
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Patterns of schizophrenia symptoms: hidden structure in the PANSS questionnaire | Translational Psychiatry
The clinical presentation of patients with schizophrenia has long been described to be very heterogeneous. Coherent symptom profiles can probably be directly derived from behavioral manifestations qua... [Read More]
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Recommendations and future directions for supervised machine learning in psychiatry | Translational Psychiatry
Machine learning methods hold promise for personalized care in psychiatry, demonstrating the potential to tailor treatment decisions and stratify patients into clinically meaningful taxonomies.  [Read More]
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Brain structure, cognition, and brain age in schizophrenia, bipolar disorder, and healthy controls | Neuropsychopharmacology
Schizophrenia and bipolar disorder (BD) may be disorders of accelerated aging. Direct comparison of healthy aging populations with schizophrenia and BD patients across the adult lifespan may help info... [Read More]
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Associations of morbidity in the underweight | European Journal of Clinical Nutrition
There is little research on the demographic characteristics and morbidity of people categorized as ‘underweight’ from their body mass index (BMI) although they have often been shown to have greater mo... [Read More]
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MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer
MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer [Read More]
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Evidence for Shared Genetic Risk Between Methamphetamine-Induced Psychosis and Schizophrenia | Neuropsychopharmacology
Methamphetamine (METH) use can provoke psychotic reactions requiring immediate treatment, namely METH-induced psychosis. Although the distinction between METH-induced and primary psychosis is importan... [Read More]
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From population to neuron: exploring common mediators for metabolic problems and mental illnesses | Molecular Psychiatry Journal
Major mental illnesses such as schizophrenia (SZ) and bipolar disorder (BP) frequently accompany metabolic conditions, but their relationship is still unclear, in particular at the mechanistic level. ... [Read More]
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Amphetamine sensitization alters hippocampal neuronal morphology and memory and learning behaviors | Molecular Psychiatry
It is known that continuous abuse of amphetamine (AMPH) results in alterations in neuronal structure and cognitive behaviors related to the reward system. However, the impact of AMPH abuse on the hipp... [Read More]
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A Brain Capital Grand Strategy: toward economic reimagination | Molecular Psychiatry
 Its core aim is to drive innovation in a Brain Economy by optimizing employee brain health and performance. Broadly, any objective working toward strengthening the global economy must focus on b... [Read More]