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Interleukin-1β (IL-1β) gene and increased risk for the depressive symptom-dimension in schizophrenia spectrum disorders
Interleukin-1β (IL-1β), as well as other cytokines, has been classically implicated in the pathophysiology of major psychiatric disorders such as schizophrenia and major depression, and recent stu... [Read More]
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Two distinct neuroanatomical subtypes of schizophrenia revealed using machine learning | Brain | Oxford Academic
Individuals with schizophrenia show heterogeneous clinical features. Using machine learning methods, Chand et al. identify two distinct and reproducible neuroan [Read More]
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Schizophrenia dimension-specific antipsychotic drug action and failure in amphetamine-sensitized psychotic-like rats
Schizophrenia dimension-specific antipsychotic drug action and failure in amphetamine-sensitized psychotic-like rats... [Read More]
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Towards an Immunophenotype of Schizophrenia: Progress, Potential Mechanisms, and Future Directions
The evidence to date, coupled with advances in immunology and genetics has afforded the field an unparalleled opportunity to investigate the hypothesis that a subset of patients with schizophrenia may... [Read More]
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Visual Perceptual and Working Memory Impairments in Schizophrenia | Psychiatry and Behavioral Health | JAMA Psychiatry | JAMA Network
Background Impairments in working memory have been proposed to underlie a broad range of cognitive deficits seen in schizophrenia. Visual working memory impairme [Read More]
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Schizophrenia Patient Outcomes Research Team (PORT): Updated Treatment Recommendations 2003 | Schizophrenia Bulletin | Oxford Academic
Since publication of the original Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations in 1998, considerable scientific advances have occurred in our knowledge about how to he... [Read More]
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Impact of emotion dysregulation and cognitive insight on psychotic and depressive symptoms during the early course of schizophrenia spectrum disorders
Impact of emotion dysregulation and cognitive insight on psychotic and depressive symptoms during the early course of schizophrenia spectrum disorders... [Read More]
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A systematic review and narrative synthesis of data-driven studies in schizophrenia symptoms and cognitive deficits | Translational Psychiatry
To tackle the phenotypic heterogeneity of schizophrenia, data-driven methods are often applied to identify subtypes of its symptoms and cognitive deficits. However, a systematic review on this topic i... [Read More]
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Social cognition and interaction training for patients with stable schizophrenia in Chinese community settings
Social cognition and interaction training for patients with stable schizophrenia in Chinese community settings... [Read More]
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Social cognitive skills training in schizophrenia: An initial efficacy study of stabilized outpatients☆
ocial cognitive deficits are promising treatment targets for new interventions to improve functional outcome in schizophrenia. A few preliminary studies of inpatients support the feasib... [Read More]
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Antipsychotic polypharmacy in patients with schizophrenia: a multicentre comparative study in East Asia
Previous studies of the prescription patterns of psychotropic medications in patients with schizophrenia have highlighted a high rate of antipsychotic polypharmacy, but data in Asia are sparse. This s... [Read More]