The chapter uses previous research to demonstrate a connection between air pollution and the severity of psychiatric conditions such as psychosis, depression, bipolar disorder, mood disorders, drug addiction, and anxiety. This link may explain the higher occurrence of psychosis in urban areas. The chapter aims to explore this relationship by examining air pollution factors such as particulate matter (PM) 2.5, nitrogen oxides (NO), and PM 10. However, the exact nature and extent of the relationship between air pollution and symptom severity in patients with schizophrenia (SCZ) is still not well understood and requires further investigation.