Brain imaging studies on Tardive Dyskinesia in schizophrenia patients and animal models: a comprehensive review
Tardive Dyskinesia (TD) is an iatrogenic movement disorder that most frequently impacts patients with schizophrenia (SCZ) who use antipsychotics (APs) for a month or longer. Although brain imaging studies focusing on TD have increased in recent decades, this research area is still underdeveloped. Prior research has shown numerous deficits associated with TD, suggesting that TD should not only be conceptualized as an abnormal movement disorder. Given the evidence of cognitive deterioration in patients with TD compared to the patients with SCZ without TD, linking cognitive deterioration with structural and physiological changes in the brain help improve assessment and prediction of cognitive changes in this population. This review examines the present literature on neuroimaging and TD and discusses key themes.
https://www.tandfonline.com/doi/full/10.1080/14796708.2024.2433936?src=exp-la#abstract
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